If you cannot configure the CRM 2011 outlook client after installing, and you receive a mapi error or .net 4 framework error…
First, Locate the MSMAPI32.dll and rename .OLD (using search)
the from the command prompt type: fixmapi
Try the CRM 2011 Outlook Client Configuration again, if it still fails to configure:
From the control panel, add/remove programs, Repair the Framework 4 which will requirs a reboot.
Also, make sure that all windows updates have been completed (might require several reboots!)